Low-density lipoproteins and atherosclerosis

 

 

The role of lipoproteins containing high cholesterol is to transport lipids to the muscles and fat stores. Cells that need cholesterol for building membranes synthesize receptors that bind low-density lipoproteins circulating in the blood. Then they absorb lipoprotein and use the cholesterol contained in it.

 

However, low-density lipoproteins are also associated with the accumulation of fatty plaques on the arterial walls, which leads to atherosclerosis and stroke.

 

High-density lipoproteins, on the other hand, appear to play an important role in protecting the body against these diseases. By circulating in the blood, they absorb unused cell cholesterol and return it to the liver, where it is processed.

 

The variety of human food is immense. For many people in the tropics, a typical daily diet consists of two small bowls of rice and a small amount of vegetables, which together gives you possibly 160 kcal and contains only a small amount of essential proteins, vitamins and minerals.However, in industrialized countries, the daily diet of an amateur can exceed 3500 kcal, which, by all estimates, approximately twice the needs of the body. Even in the country average there are huge differences. In Ghana, where the diet consists predominantly of roots, cereals and vegetables, the average daily dose is probably 90% of the need, including 47 g of proteins, of which only 11 are of animal origin. In Denmark, where meat, dairy products, grains, vegetables and fruits form the basis of the diet, the average dose is 130% of the needs, including 95 g of proteins (62 animals). The diet also varies significantly in diversity, range of geographic sources, and treatment before use. Probably, in 75% of the world's population, the diet consists of one main product, usually grain crops (mainly rice), which grows by itself and is usually eaten in a simple cooked form. The average grain consumption with such a diet is approximately 180 kg per year per person. As a contrast, we note that in North America about 800 kg of grain per person are included in the food chain annually, but only 30% of them are consumed as grain products. The rest goes to feed livestock for the production of meat and milk.People in developed countries buy a lot of food in restaurants, takeaway food stores and vending machines. The average supermarket has 7,000 different food items that are stored, transported (possibly imported), usually processed and preserved and wrapped for sale. As a result of this abundance in the United States, where the daily calorie intake averages 130% of the need, according to statistics from the World Health Organization, in the late 1980s, 12% of men and 15% of women were obese.



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